Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Rho guanine nucleotide exchange factor 7 (RAC1 guanine nucleotide exchange factor (GEF))

Seq-ID:

Q14155 [Homo sapiens]

Download:

Interaction Network(s):

STRING

External Source(s):

Phosida

Phosida

MINT Interaction(s):

[show]

MINT-19486   PAK1_MOUSE
MINT-19869   GIT2_MOUSE
MINT-56632   CBLB_HUMAN
MINT-1953461   GIT2_HUMAN
MINT-2792601   ADA15_HUMAN
MINT-3372015   CDC42_HUMAN
MINT-3374907   CD244_HUMAN
MINT-7145306   RAC1_HUMAN
MINT-7147251   PAK2_HUMAN
MINT-7147263   GIT1_HUMAN
MINT-7210792   SCRIB_HUMAN
MINT-7211864   CBL_HUMAN
MINT-7212697   PAK1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
Rho guanyl-nucleotide exchange factor activity, protein binding	cytosol	induction of apoptosis by extracellular signals, apoptosis, regulation of Rho protein signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	518	LLMLSASPRMSGFIYQGKLPT	-	18220336	HTP	1.00		-	PH	0.31	-	medium
S	694	LPKRKPERKPSDEEFASRKST	-	18669648	HTP	1.00		-	-	0.80	-	medium

Rho guanine nucleotide exchange factor 7 (RAC1 guanine nucleotide exchange factor (GEF))

Seq-ID:

Q14155-1 [Homo sapiens]

Download:

Interaction Network(s):

-

External Source(s):

Phosida

MINT Interaction(s):

MINT-56630 CBLB_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
Rho guanyl-nucleotide exchange factor activity, protein binding	cytosol	induction of apoptosis by extracellular signals, apoptosis, regulation of Rho protein signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	516	LPKRKPERKPSDEEFASRKST	PKA_group	15513924	LTP	1.00	MOD_PKA_1	-	-	0.80	-	medium
T	526	SDEEFASRKSTAALEEDAQIL	PKA_group	15513924	LTP	1.00	MOD_PKA_1	-	-	0.59	-	medium

Rho guanine nucleotide exchange factor 7 (RAC1 guanine nucleotide exchange factor (GEF))

Seq-ID:

Q9ES28 [Mus musculus]

Download:

Interaction Network(s):

-

External Source(s):

Phosida

Phosida

MINT Interaction(s):

-

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
Rho guanyl-nucleotide exchange factor activity, protein binding		positive regulation of apoptosis, regulation of Rho protein signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	155	TSKLLQSQYRSLDMTDNTNSQ	-	17242355	HTP	1.00		-	-	0.47	-	medium
S	497	LLMLSASPRMSGFIYQGKLPT	-	15345747	HTP	1.00		-	PH	0.31	-	medium
S	497	LLMLSASPRMSGFIYQGKLPT	-	17114649	HTP	1.00		-	PH	0.31	-	medium
S	673	LPKRKPERKPSDEEFAVRKST	-	15572359	HTP	1.00		-	-	0.75	-	medium
S	682	PSDEEFAVRKSTAALEEDAQI	-	12226077	LTP	0.98		-	-	0.58	-	medium
T	683	SDEEFAVRKSTAALEEDAQIL	-	12226077	LTP	0.97		-	-	0.54	-	medium

Rho guanine nucleotide exchange factor 7 (RAC1 guanine nucleotide exchange factor (GEF))

Seq-ID:

Q9ES28-2 [Mus musculus]

Download:

Interaction Network(s):

External Source(s):

Phosida

MINT Interaction(s):

[show]

MINT-1786487 SHAN3_RAT
MINT-1786531 SHAN1_RAT

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
Rho guanyl-nucleotide exchange factor activity, protein binding		positive regulation of apoptosis, regulation of Rho protein signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	228	REIKPSEKPVSPKSGTLKSPP	-	19144319	HTP	1.00		-	-	0.71	-	medium

Rho guanine nucleotide exchange factor 7 (RAC1 guanine nucleotide exchange factor (GEF))

Seq-ID:

Q9ES28-3 [Mus musculus]

Download:

Interaction Network(s):

External Source(s):

Phosida

MINT Interaction(s):

-

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
Rho guanyl-nucleotide exchange factor activity, protein binding		positive regulation of apoptosis, regulation of Rho protein signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	497	LLMLSASPRMSGFIYQGKLPT	-	19144319	HTP	1.00		-	PH	0.33	-	low
S	598	LPKRKPERKPSDEEFAVRKST	-	19144319	HTP	1.00		-	-	0.71	-	low